Table 2 Results regarding activation timing from TD: active > passive.

From: Temporal characteristics of hemodynamic responses during active and passive hand movements in schizophrenia spectrum disorder

Cluster label

Cluster extends

X

Y

Z

T

ZE

kE

PFWE-coorr.

Common activation timing in HC and SSD: HC (active>passive) ∩ SSD (active>passive)

Left precentral gyrus

PreCG_L (61.4%), PoCG_L (24.4%), PCL_L (5%), Not assignable (9.1%)

−22

−26

60

5.19

5.07

472

0.189

Right precentral gyrus

PreCG_R (39%), PoCG_R (17.6%), PCL_R (3%), Not assignable (39.9%)

22

−26

58

5.09

4.98

336

0.401

Left supplementary motor area

SMA_L (41.4%), SMA_R (25.2%), MCC_R (18%), MCC_L (14.3%)

6

8

50

4.83

4.74

894

0.020

Right fusiform gyrus

FFG_R (50.3%), CER6_R (30.4%), CERCRU1_R (5.6%)

34

−62

−18

4.43

4.36

611

0.088

Right putamen

PUT_R (23.6%), INS_R (17.6%), IFGorb_R (8.9%), THA_R (12.4%), PAL_R (5.9%), IFGoperc_R (5.4%), Not assignable (21.5%-),

50

20

−4

4.28

4.21

573

0.108

Left cuneus

CUN_L (20.4%), SOG_R (19.4%), SOG_L (14.7%), PCUN_L (13.3%), CUN_R (13.1%), MOG_R (9%), MOG_L (5.6%)

8

−88

28

4.12

4.06

1242

0.004

Left putamen

PUT_L (42.2%), PAL_L (32.3%), Not assignable (22.4%)

−26

−12

0

3.93

3.87

232

0.669

Right middle temporal gyrus

MTG_R (86.4%), ITG_R (6.6%), MOG_R (6.3%)

56

−56

8

3.62

3.58

301

0.482

Right precentral gyrus

PreCG_R (52.8%), IFGoperc_R (34.4%), MFG_R (12.8%)

46

12

36

3.58

3.54

180

0.817

Lobule VI of left cerebellar hemisphere

CER6_L (48.4%), FFG_L (37.7%), CERCRU1_L (13.9%)

−40

−66

−20

3.32

3.28

122

0.944

Right supramarginal gyrus

SMG_R (83.7%), PoCG_R (12.7%)

60

−16

24

3.26

3.23

110

0.961

HC specific activation for self-generated movement in HC: HC (active>passive) > SSD (active>passive) masked by HC (active>passive)

Right cuneus

CAU_R (46.7%), PUT_R (11%), THA_R (6%), Not assignable (35.7%)

26

8

14

4.51

4.44

700

0.054

Left superior temporal gyrus

STG_L (52.1%), INS_L (32.1%), TPOsup_L (7.3%), ROL_L (5.5%)

−50

0

−2

4.27

4.21

165

0.855

Lobule VIII of right cerebellar hemisphere

CER8_R (32.3%), CER7b_L (19.5%), CER7b_R (12.3%), CER8_L (11.8%), VER8 (6.2%), Not assignable (17.4%)

−2

−76

−44

4.20

4.14

195

0.776

Left postcentral gyrus

PoCG_L (77.1%), PreCG_L (22.9%)

−48

−16

56

3.81

3.76

140

0.912

Left thalamus

THA_L (14.8%), THA_R (9.4%), CAU_L (7.2%), Not assignable (46.5%)

−4

−14

14

4.10

4.04

747

0.042

Left superior temporal gyrus

STG_L (91.4%), MTG_L (%5.9)

−48

−20

6

3.67

3.63

186

0.801

Left putamen

PUT_L (53.7%), INS_L (10.4%), PAL_L (5.7%), Not assignable (27.6%)

−28

−8

14

3.36

3.33

192

0.784

Interaction effect: HC ([Selfact-Selfpas]-[Otheract-Otherpas8]) > SSD ([Selfact-Selfpas]-[Otheract-Otherpas])

Left insula

INS_L (49.8%), ROL_L (17.8%), PUT_L (9.6%), Not assignable (19.7%)

−38

−4

16

5.03

4.93

669

0.064

Left postcentral gyrus

PoCG_L (79.2%), SMG_L (20.8%)

−62

−10

36

4.21

4.15

226

0.687

Right insula

INS_R (37.8%), IFGoperc_R (9.8%), PUT_R (8.4%), Not assignable (42.1%)

36

12

14

4.10

4.05

225

0.690

Left superior frontal gyrus

SFG_L (50%), MFG_L (49.4%)

−24

36

30

3.90

3.85

172

0.838

HC specific interaction effect for self-generated movement: HC ([Selfact-Selfpas]-[Otheract-Otherpas]) > SSD ([Selfact-Selfpas]-[Otheract-Otherpas]) masked by HC ([Selfact-Selfpas]-[Otheract-Otherpas])

Left insula

INS_L (47.6%), PUT_L (23.1%), ROL_L (11.2%), Not assignable (23%)

−38

−4

16

5.03

4.93

338

0.397

Right insula

INS_R (40.2%), PUT_R (13.9%), IFGoperc_R (5.1%), Not assignable (39.4%)

36

10

14

3.76

3.72

137

0.918

Specific interaction effect for self-active movement and own hand feedback in HC: HC ([Selfact-Selfpas]-[Otheract-Otherpas]) > SSD ([Selfact-Selfpas]-[Otheract-Otherpas]) masked by HC Self-active

Left insula

INS_L (61.8%), PUT_L (5%), ROL_L (8.6%), Not assignable (21.8%)

−32

8

2

4.66

4.57

280

0.536

Right insula

INS_R (46%), IFGoperc_R (17.7%), PUT_R (7.3%), Not assignable (27.4%)

36

12

14

4.10

4.05

124

0.941

Interaction effect: SSD([Selfact-Selfpas]-[Otheract-Otherpas]) > HC ([Selfact-Selfpas]-[Otheract-Otherpas])

Left precentral gyrus

PreCG_L (65.1%), SFG_L (34.9%)

−28

−14

72

4.15

4.09

149

0.893

Left supplementary motor area

SMA_L (53.4%), PCL_L (26.2%), SMA_R (17.7%)

−6

−14

66

4.07

4.02

221

0.701

Left postcentral gyrus

PoCG_L (83%), PreCG_L (10.2%), SPG_L (6.2%)

−40

−34

64

3.84

3.79

176

0.827

  1. Coordinates are listed in MNI space and used AAL 3v1 cluster labelling. Cluster defining threshold: p < 0.005, uncorrected, minimum cluster size = 104 voxels (Monte−Carlo cluster level corrected at p < 0.05). (Note: FWE-Cluster-corrected values are provided in Table 2); R = right hemisphere; L = left 384 hemisphere.
  2. CAU caudate nucleus, PreCG precentral gyrus, PoCG postcentral gyrus, SFG superior frontal gyrus, MFG middle frontal gyrus, SMG supra-marginal gyrus, PUT lenticular nucleus, putamen, INS Insula, PAL lenticular nucleus, pallidum, THA thalamus, ROL Rolandic operculum, SMA supplementary motor area, MCC middle cingulate & paracingulate gyri, STG superior temporal gyrus, MTG middle temporal gyrus, ITG inferior temporal gyrus, CUN cuneus, SOG superior occipital gyrus, MOG middle occipital gyrus, FFG fusiform gyrus, PCUN precuneus, SPG superior parietal gyrus, TPOsup temporal pole, superior temporal gyrus, IFGoperc inferior frontal gyrus, opercular part, IFGorb inferior frontal gyrus, orbitalis, PCL paracentral lobule, CERCRU1 crus I of cerebellar hemisphere, CER6 lobule VI of cerebellar hemisphere, CER7b Lobule VIIB of cerebellar hemisphere, CER8 lobule VIII of cerebellar hemisphere, VER8 lobule VIII of vermis.
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