Table 1 Currently reported miRNAs involved in the macrophage cholesterol metabolism and inflammation in the progression of atherosclerosis

From: Dietary compounds have potential in controlling atherosclerosis by modulating macrophage cholesterol metabolism and inflammation via miRNA

Function

miRNAs

Targets

Reference

 

miR-125a-5p

LOX-1, CD68

37

Cholesterol metabolism

miR-155

LOX-1, CD36, CD68

38

miR-467b

ACAT1

39

miR-9

ACAT1

40

miR-134

ANGPTL4

41

miR-467b

LPL

42

miR-33

ABCA1

45, 46

miR-19b

ABCA1

8

miR-144, -26, -27a, -758, -148a

ABCA1

52-55

miR-10b

ABCA1, ABCG1

56, 57

miR-378

ABCG1

58

Inflammation

miR-146a

IRAK1, TRAF6

36, 88

miR-155

SMAD2, FOXO3a, SOCS1, SHIP1, BCL6

19, 87, 11

miR-125a-5p

Unknown

37

miR-467b

Unknown

42

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