Fig. 10: FMT from the 0.6-Se group activated the Nrf2 signaling pathway to inhibit the diquat-induced intestinal mitochondrial dysfunction. | npj Science of Food

Fig. 10: FMT from the 0.6-Se group activated the Nrf2 signaling pathway to inhibit the diquat-induced intestinal mitochondrial dysfunction.

From: Dietary supplementation with biogenic selenium nanoparticles alleviate oxidative stress-induced intestinal barrier dysfunction

Fig. 10

a, b ROS production was determined by DHE staining (n = 7). c Mitochondrial ultrastructure was observed by TEM. d Mitochondrial ATP level in the jejunal mitochondria (n = 6). e MMP was measured by JC-1 staining in the jejunal mitochondria (n = 6). f Level of 8-OHdG in the jejunal mitochondria (n = 6). g The mtDNA copy number was analyzed by qPCR (n = 6). h The mRNA expression levels of TFAM, POLG, and POLG2 in the jejunum (n = 6). i The expression levels of NLRP3 inflammatory protein were measured by Western blot analysis (n = 3). j Nrf2 activation and expression levels of its downstream proteins measured by Western blot analysis (n = 3). Data are expressed as the fold change versus the control group (set to 1). Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001.

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