Fig. 4: Effects of different dietary SeNPs supplementation on jejunal mitochondrial dysfunction in diquat-exposed mice.

a, b ROS production was determined by DHE staining (n = 6). c Mitochondrial ultrastructure was observed by TEM. d Mitochondrial ATP levels in the jejunal mitochondria (n = 8). e MMP was measured by JC-1 staining in the jejunal mitochondria (n = 8). f Levels of 8-OHdG in the jejunal mitochondria (n = 8). g The mtDNA copy number was determined by qPCR analysis (n = 6). h mRNA expression level of TFAM in the jejunum (n = 6). i mRNA expression level of POLG in the jejunum (n = 6). j mRNA expression level of POLG2 in the jejunum (n = 6). Data are expressed as the fold change versus the 0.3-Se group or 0.3-Se + diquat group (set to 1). Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001.