Fig. 6: The Nrf2 signaling pathway inhibits the diquat-induced NLRP3 inflammasome activation in the jejunum.

a The expressions of the NLRP3 inflammatory proteins were measured by Western blot analysis (n = 3). b Quantitative analysis of the protein expression levels of NLRP3, ASC, pro-caspase 1, cleaved-caspase 1, IL-1β, and IL-18. c Nrf2 activation and expression levels of its downstream proteins were measured by Western blot analysis (n = 3). d Quantitative analysis of the protein expression levels of total Nrf2, nuclear Nrf2, HO-1, and NQO-1. Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001.