Fig. 3: Comparison of gut microbial metagenomic functions between FHVD (n = 8) and NFHVD (n = 8).

Changes in (a) Venn diagram of the gene counts. PCA (Principal Components Analysis) plot of (b) NFHVD and (c) FHVD based on Bray–Curtis distance according to KEGG Ontology (KO) profiles. (d) Microbial metabolic module alternation in FHVD and NFHVD. Asterisk denotes reporter score (RS) of module > 1.65 or < −1.65 were considered to be significant. Pink, enriched by after intervention; Blue, enriched before intervention.