Fig. 2: The number of differentially expressed genes (DEGs) and differentially expressed proteins (DEPs) between L. paracasei Zhang ΔpglX (mutant) and wild-type freeze-dried cells stored for 30 and 60 days.

Venn diagram and histogram (A) show the number of DEGs in freeze-dried cells stored for 30 and 60 days. Gene sets of up- and down-regulated DEGs after 30 or 60 days of storage are represented as “30 up”, “30 down”, “60 up”, and “60 down”, respectively. Volcano plots of DEPs between the mutant and wild-type after (B) 30 days and (C) 60 days of storage are presented. The x- and y-axes show the fold change and p-value of the comparison between the two cell lines, respectively. Each dot in the figure represents a specific protein; grey, blue, and red dots represent non-significant, significantly upregulated, and down-regulated DEPs, respectively (cut-off level: |FC | ≥ 1.5; p ≤ 0.05). The number of non-significant, significantly up- regulated, and down-regulated DEPs is indicated in the suffix of the label.