Fig. 6: Erythritol exposure causes thrombosis in zebrafish larvae.

A Representative images of o-dianisidine staining in control and different concentrations of erythritol groups. The heart regions and tail regions are delineated by a red dotted line. B Quantitative analysis of the intensity of cardiac erythrocytes. C, D Relative mRNA expression of coagulation factor II (f2) and fibrinogen β chain (fgb). E Schematic diagram of platelet aggregation due to increased expression of the rev-erba gene. Some of the material in (E) has been taken from Figdraw, with permission from Figdraw (license code: zzSSS0bb64). The image is created by the author, and there is no copyright or conflict of interest. F Relative mRNA expression of oligophrenin-1 (ophn1). G Relative mRNA expression of rhoa. H Relative mRNA expression of ezrin. Data are represented as mean ± SD. N = 3; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.