Fig. 7: Erythritol induces oxidative stress and inflammation.

Representative pictures (A) and quantifications (B) of the DCFH-DA stained fluorescence signals in various exposure groups. C–E The relative mRNA expression of oxidative stress-related genes in larval zebrafish, such as sod1 (C), cat (D), gpx1 (E). F–I The zebrafish larvae’s relative mRNA expression of genes related to inflammation, such as the pro-inflammatory factors IL-6 (F) and IL1-β (G), as well as the anti-inflammatory factors IL-10 (H), and IL-4 (I). Data are represented as mean ± SD. N = 3; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.