Table 2 Results of transcriptomic significance pathway enrichment analysis in Caco-2 cells
Serial number | Primary access | Secondary access | Pathway description | P value | Number of key metabolites |
|---|---|---|---|---|---|
1 | Organism System | Endocrine System | Glucagon signaling pathway | 0 | 5 |
2 | Metabolism | Nucleotide Metabolism | Purine Metabolism | 0 | 14 |
3 | Metabolism | Global and overview diagrams | Nucleotide Metabolism | 0 | 14 |
4 | Environmental Information Processing | Signal Transduction | FoxO signaling pathway | 0 | 3 |
5 | Organismal Systems | Sensory System | Taste transduction | 0 | 6 |
6 | Metabolism | Global map and overview | Cofactor biosynthesis | 0 | 17 |
7 | Metabolism | Amino Acid Metabolism | Alanine, aspartate, and glutamate metabolism | 0 | 6 |
8 | Human Diseases | Cancer: Overview | Central carbon metabolism in cancer | 0 | 8 |
9 | Metabolism | Carbohydrate Metabolism | Glyoxalate and dicarboxylic acid metabolism | 0 | 7 |
10 | Metabolism | Carbohydrate Metabolism | Citric acid cycle (TCA cycle) | 0.0001 | 4 |
11 | Organismal Systems | Nervous System | GABAergic synapses | 0.0002 | 3 |
12 | Environmental Information Processing | Signal Transduction | cGMP-PKG signaling pathway | 0.0003 | 3 |
13 | Environmental Information Processing | Membrane Transport | ABC transporter proteins | 0.0006 | 8 |
14 | Environmental Information Processing | Signaling molecules and interactions | Neuroactive ligand-receptor interactions | 0.0007 | 5 |
15 | Metabolism | Energy Metabolism | Sulfur metabolism | 0.001 | 4 |
16 | Metabolism | Energy Metabolism | Oxidative phosphorylation | 0.0012 | 3 |
17 | Organismal systems | Excretory System | Proximal tubular bicarbonate recycling | 0.0015 | 3 |
18 | Organismal systems | Endocrine System | Renin secretion | 0.0015 | 3 |
19 | Human Disease | Cardiovascular Disease | Diabetic cardiomyopathy | 0.0019 | 4 |
20 | Organism system | Endocrine system | Aldosterone synthesis and secretion | 0.0032 | 3 |
