Fig. 4: Effects of inflammation by PVSO in 4T1 tumor-bearing mice.

A, B Serum TNF-a and IL-1β levels (n = 4). C–E Inflammatory factor expression levels in the prefrontal cortex (n = 4). F–I Inflammatory factor expression levels in the hypothalamus. J–K Representative western blots of NF-κB (n = 3). Data are presented as mean ± SEM, *P < 0.05, **P < 0.01, ***p < 0.001 by One-way ANOVA (n = 3–4 per group).