Fig. 4
From: Meta-analysis of host response networks identifies a common core in tuberculosis
The Tier-2 common core depicting highly active nodes and their corresponding pathways enriched in disease. The STAT-1 centric responses are retained at Tier 2 and the emergence of other well connected hubs such as MAPK1 and SP1 is also observed, encompassing myriad signalling processes and their crosstalk across multiple cell and tissue types, captured in the whole blood milieu. Genes reported to have SNPs in different studies ascribing susceptibility to tuberculosis are marked in red in this network
