Table 2 Abbreviations used in this manuscript

SRG

Various

Differentially expressed gene identified by ANOVA time series analysis. SRGs(n) refers to the DEGs conserved in at least n data sets, n = 1,2,…,12

JTG

Various

Gene showing significant up- or down-trend across the time series identified by Jonckheere trend analysis. JTGs(n) refers to the genes with up-trend or down-trend in at least n data sets, n = 1,2,…,12

sgDOCK5-DEGS

Various

Gene signatures differentially expressed during influenza infection scenarios between DOCK5-wt and DOCK5-ko experiments (fold change ≥ 1.2 or ≤ 1/1.2 FDR < 0.05)

sgDOCK5-DEG⁺

2863

A gene signature up-regulated by DOCK5 knockout (i.e., genes repressed by DOCK5) after H3N2 infection (absolute values used, fold change ≥ 1.2, FDR < 0.05)

sgDOCK5-DEG^-

4512

A gene signature down-regulated by DOCK5 knockout (i.e., genes activated by DOCK5) after H3N2 infection (absolute values used, fold change ≤ 1/1.2, FDR < 0.05)

DOCK5-CCGS(n)

Table S12

Genes correlated with DOCK5 in at least n data sets, n = 2, 3,…, 12

GO

4653

Gene ontology of biological processes (BP)¹⁹

MSigDB

1329

Molecular signatures database, curated, canonical processes (c2.cp)²⁰

Watanabe

129

Host-factors identified after consensus siRNA studies⁵

Ward

280

Targets after siRNA studies by Ward et al.²¹

Inflammatome

2483

Inflammatome gene set²²

ISG

395

Interferon Stimulated Genes from the Interferome database²³

InnateDB

1371

Genes from InnateDB²⁴