Table 1 Centrality of diseases in diseasomes, calculated as the degree centrality of each disease within diseasomes and average centrality across four diseasomes
Disease | Gene network degree | Interaction network degree | Symptom network degree | Comorbidity network degree | Average degree |
|---|---|---|---|---|---|
Stroke | 10 | 10 | 2 | 7 | 7.25 |
Alzheimer disease | 6 | 9 | 1 | 5 | 5.25 |
Dementia | 6 | 10 | 3 | 0 | 4.75 |
Atherosclerosis | 3 | 6 | 0 | 8 | 4.25 |
Asthma | 3 | 7 | 1 | 5 | 4 |
Diabetes mellitusa | 6 | 10 | 0 | 0 | 4 |
Parkinson disease | 3 | 7 | 2 | 4 | 4 |
Heart Failure | 1 | 4 | 2 | 7 | 3.5 |
Migraine Disorders | 1 | 7 | 0 | 5 | 3.25 |
Myocardial Infarction | 4 | 7 | 2 | 0 | 3.25 |
Hypertension | 1 | 3 | 1 | 7 | 3 |
Obesity | 2 | 4 | 0 | 6 | 3 |
