Fig. 3

Transcriptome co-annotation. a Human best-match of genes co-annotated between H. Magnipapillata (HM), S. Mediterranea (SM), and A. Japonicus (AJ). Most of these genes are also ortholog in mouse and annotated in axolotl. b The subset of human genes that are both co-annotated and differentially expressed in all the three considered organisms have a small superimposition with genes differentially expressed during mouse and axolotl regenerations. c Panther annotation of relevant biological processes, molecular function, and pathways of the 18 human best-match proteins that are both co-annotated and differentially expressed in H. Magnipapillata, S. Mediterranea, and A. Japonicus