Fig. 2

Blood glucose, GFR, and UAER over time in db/db mice with or without uninephrectomy (UNX–performed between 8–10 weeks of age), compared to WT or db/m mice. Data were obtained from published studies (Huang 2008,¹² Levine 2006,⁴⁶ Levine 2008,¹³ Bivona 2011,²¹ Sun 2016,⁴⁷ Ward 2017,⁴⁸ Wang 2017,⁴⁹ and Fan 2017⁵⁰) and unpublished AstraZeneca reports of additional studies conducted according to protocols of Huang 2008¹²