Fig. 4 | npj Systems Biology and Applications

Fig. 4

From: Parsimonious Gene Correlation Network Analysis (PGCNA): a tool to define modular gene co-expression for refined molecular stratification in cancer

Fig. 4

Module neighborhoods provide fine-grained resolution. Neighborhoods within modules are displayed by color code, interactive version online. a CRC_M3, enterocyte module, expanded: CRC_M3.n9, WNT-signaling (blue), and CRC_M3.n1, superficial enterocyte (orange). b CRC_M7, goblet metabolic module, expanded: CRC_M7.n8, classical goblet cell and CMS3 genes (purple), and CRC_M7.n1 putative deep secretory cell neighborhood (dark pink). c BRCA_M14, basal/normal module, expanded: BRCA_M14.n8 (blue), basal classifier genes, and BRCA_M14.n7 (pink), epithelial/epidermal differentiation. d BRCA_M6, luminal module, expanded: BRCA_M6.n8, GATA3 and ESR1 neighborhood (yellow). Related GSE results in Supplemental Fig. 12

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