Fig. 5 | npj Systems Biology and Applications

Fig. 5

From: Parsimonious Gene Correlation Network Analysis (PGCNA): a tool to define modular gene co-expression for refined molecular stratification in cancer

Fig. 5

Networks as multilayered tools to explore survival association. BRCA (a) and CRC (b) meta-information overlay. Left to right: module color code, median expression percentile (relative intensity of expression) across data-sets, median expression dispersion (Quartile coefficient of dispersion, variation between samples/patients) within data-sets, and association of gene expression with meta-analysis Hazard Ratio (HR) of death. Color scales: expression dispersion and variance blue (least) to red (most); outcome blue (low HR—good outcome) to red (high HR—poor outcome). Lower panels ranked module level association with meta HR of death. Distribution of HR associations for module genes with HR p-value <0.05, along with median (blue square) and IQR

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