Fig. 1 | npj Systems Biology and Applications

Fig. 1

From: An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian cells

Fig. 1

Effects of raw and averaged specific uptake constraints on growth rate predictions when using biomass objective function compared to experimental growth measurements for 7 replicates. a Schematic of different GeM growth predictions with raw or averaged data inputs of lysine, histidine, lysine plus histidine, and glucose; b growth rate measurements (yellow bars) versus growth rate predictions (black bars) before and after specific input averaging; c mean relative deviation of predicted grow rates using replicate 1–7 inputs compared to predicted growth rate using averaged inputs for all five raw/modified datasets; d deviation from “average” is defined as the difference between predicted growth rates using replicate and averaged inputs

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