Fig. 2
From: Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types
High stress differential coexpression modules across 14 cancer types. Differential coexpression modules were obtained for high stress vs. low-stress samples using differential coexpression analysis14,15 for 15 cancer types. No modules were found for prostate. The differential coexpression modules were mapped to a physical human protein interactome.19 In addition, differential gene expression was performed on the same stress groups. The brown and turquoise fractions illustrate significant differentially up or down expressed genes, respectively. Darker areas are genes that participate in a physical protein–protein interaction. Grey areas are genes that are not differentially expressed. Numbers within each bar are the number of genes per module. DE: differential expression; PPI: protein–protein interaction
