Fig. 3: Agent-based models can be used to model complex signalling networks.

The network of reactions in the model of apoptosis execution is shown a. ABM simulations (thin solid lines) of apoptosis execution were compared to equivalent ODE simulations (thick grey lines) for final substrate cleavage (b). All simulations were for 30 min, the time step Δt for particle diffusion was 0.0001 s and for reactions was 0.05 s in all simulations. Data in b represents mean +/− range (thin grey lines) from three independent simulations.