Fig. 4: A comparative visualisation of the DEGs between the two approaches for the T1D pathway in all three analyses.
From: A personalised approach for identifying disease-relevant pathways in heterogeneous diseases
a DEGs from T1D pathway in the TC analysis using Dataset 1, (b) DEGs from T1D pathway in the WSC analysis using Dataset 1 and (c) DEGs from T1D pathway in the WT1D analysis using Dataset 2. A coloured dot signifies that the gene is DE in the corresponding case-control pair. Here, the HLA genes from MHC classes I and II are not marked individually, but grouped into their two major classes for convenience; and a class is shown as DE in a case-control pair when at least one probe-set from any HLA gene of the class was found DE in that pair. Also, pairs from Dataset 1 and Dataset 2 are prefixed with ‘SC-’ and ‘T1D-’, respectively.
