Table 2 Number of enriched pathways overlapping between different approaches in the TC, WSC and WT1D analyses (rows marked as ‘count’). A p-value, determined using Fisher’s exact test, is also given for each overlap to show its significance (rows marked as ‘p-value’), where NS refers to ‘not significant’ p-values (i.e., p-value > 0.05). Fisher’s combined p-value over all analyses per comparison is given in the last column.
From: A personalised approach for identifying disease-relevant pathways in heterogeneous diseases
Overlaps/analyses | TC | WSC | WT1D | Fisher’s combined p-value | |
|---|---|---|---|---|---|
Combined method vs. personalised approach | Count | 12 | 1 | 38 | <0.0001 |
p-value | <0.0001 | NS | <0.0001 | ||
Kallionpää et al. vs. personalised approach | Count | 29 | 60 | 507 | <0.0001 |
p-value | <0.0001 | <0.0001 | <0.0001 | ||
Kallionpää et al. vs. combined method | Count | 5 | 0 | 5 | NS |
p-value | <0.01 | NS | NS |
