Fig. 5: Correlation between JSD and phenotypic plasticity across EMP networks. | npj Systems Biology and Applications

Fig. 5: Correlation between JSD and phenotypic plasticity across EMP networks.

From: Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach

Fig. 5

a Venn diagrams showing the extent of overlap among the perturbed networks that have the highest JSD from the “wild type” network and those with the highest or lowest fold change in plasticity scores (PS2). EMP networks shown are (from left to right): GRHL2, OVOL, NRF2 and OCT4. b Scatter plots for respective EMP networks. Each blue dot in a scatter plot is a perturbed network topology corresponding to that EMP network. Spearman correlation coefficient (ρ) are denoted; ***p < 0.001.

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