Table 2 Candidate epigenes for drug development in modules 4, 6, 8, and 10–12.
From: Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection
Target protein | Module | Function |
|---|---|---|
MOV10 | Module 12 | Epifactor (chromatin remodeling) |
MTA1 | Module 4 | Epifactor (chromatin remodeling cofactor) |
TLE1 | Module 12 | Epifactor (chromatin remodeling, histone modification cofactor) |
TAF4 | Module 12 | Epifactor (histone chaperone) |
BAP1 | Module 4 | Epifactor (histone modification erase, polycomb group (PcG) protein) |
TRIM28 | Module 4 | Epifactor (histone modification read) |
PRDM1 | Module 12 | Epifactor (histone modification write cofactor) |
SETD1B | Module 6 | Epifactor (histone modification write) |
UBE2D3 | Module 10 | Epifactor (histone modification write) |
PCGF5 | Module 12 | Epifactor (polycomb group (PcG) protein) |
STAT2 | Module 12 | TF |
GMEB2 | Module 6 | TF |
ZNF277 | Module 10 | TF |
IRF7 | Module 11 | TF |
CEBPD | Module 12 | TF |
NR4A1 | Module 12 | TF |
ZNF652 | Module 12 | TF |
IRF2 | Module 12 | TF |
ZEB2 | Module 12 | TF |
SP110 | Module 12 | TF |
CUX1 | Module 12 | TF |
TRIM25 | Module 12 | E3 ubiquitin ligase |
