Fig. 8: Flowchart of the proposed GCM algorithm that enables frequent, dynamic, and personalized TIC treatment. | npj Systems Biology and Applications

Fig. 8: Flowchart of the proposed GCM algorithm that enables frequent, dynamic, and personalized TIC treatment.

From: Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy

Fig. 8

This algorithm systematically recommends coagulation factor concentrations to move a patient CAT trajectory toward normal, while also maintaining concentration values within normal activity ranges. This algorithm serves as the controller block in Fig. 1a.

Back to article page