Table 1 Ligands in ligand–receptor interactions in the colon and ileum.
From: Mapping the epithelial–immune cell interactome upon infection in the gut and the upper airways
Tissue | Direction | Number | Ligands |
|---|---|---|---|
Colon only | Upregulated | 1 | FAS |
Colon only | Downregulated | 13 | CALM3, APP, AREG, LAMB3, LRPAP1, IL32, CD47, HSP90AA1, CD55, LAMC2, HLA-E, LGALS3BP, PLAUR |
Ileum only | Upregulated | 15 | EDN2, CXCL8, CX3CL1, CFLAR, CSF1, EDN1, TNFSF13B, TNFSF10, EFNA1, PLAU, CCL5, CXCL11, BMP2, BST2, IFNL1 |
Ileum only | Downregulated | 8 | MDK, SPTAN1, ARPC5, FAM3C, GRN, DSC2, CALR, LYZ |
Colon and ileum | Upregulated | 5 | CXCL2, CXCL10, ICAM1, CXCL3, TNF |
Colon and ileum | Downregulated | 16 | PI3, SLPI, HLA-A, CDH1, CALM2, S100A6, HSP90B1, TIMP2, RTN4, ADAM9, HLA-B, HLA-C, ANXA1, CALM1, PSAP, B2M |
