Fig. 4: Performance evaluation for drug indication prediction.
From: Regulome-based characterization of drug activity across the human diseasome
a Difference between the prediction scores for approved drugs and those for other drugs by the transcriptome-based prediction. b Distribution of prediction scores for approved and other drugs by the transcriptome-based prediction. c Difference between the prediction scores for approved drugs and those for other drugs by the regulome-based prediction. d Distribution of prediction scores for approved and other drugs by the regulome-based prediction. The positive difference means the prediction scores for approved drugs are larger than those for other drugs. Bars are colored according to the ICD-11 disease chapters. All P-values were determined by the Wilcoxon signed-rank test. In the box plots: center line, median; box, interquartile range; whiskers, 1.5× interquartile range; dots, outliers.
