Fig. 5: Experimental validation of predicted anticancer effects of drugs.
From: Regulome-based characterization of drug activity across the human diseasome
a List of tested drugs and their chemical structures. b The effect of an anti-endometriosis drug, danazol, on the viability of nonsmall cell lung cell lines. c The effect of danazol on the apoptosis induction. Cell lines were treated with various concentrations of danazol. The horizontal axis represents the concentration on a logarithmic scale. The vertical axis represents the relative viability and relative apoptosis induction (caspase activity). Plot shows means and standard deviations for triplicate experiments.
