Fig. 7: Cell numbers in the three cell types’ system with various regulation powers (i.e., various γ values) between cell type 3 and the other two cell types.
From: ‘Social’ versus ‘asocial’ cells—dynamic competition flux balance analysis
a: \(\gamma =0\) (no such cross regulation). b: \(\gamma =0.2\). c: \(\gamma =0.3.\) d: \(\gamma =0.4.\) The inherent growth rate bias in favor of cell type 2 as compared to the other two cell types was taken to equal \(\beta =0.05\). We calculated over a longer time (i.e., t = 200 months) to show the steady state. The stepwise growth algorithm in the three cell types’ system with cross-regulation power of 1 (i.e., \(\varepsilon =1\)) between cell type 1 and type 2 and also only regulation to the third cell type from the other two cell types was used for the stepwise-growth FBA computations with maximal total biomass synthesis as objective and with maximum metabolic production capacity in place.
