Fig. 2: PhysiBoSS 2.0 add-on-based design.
From: PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks

a shows a diagram of the add-on-based design of PhysiBoSS 2.0 that decouples PhysiCell and MaBoSS providing Boolean simulation functionality to individual cell agents in a maintainable manner. b depicts a high-level view of the PhysiCell and PhysiBoSS 2.0 and the communication between the different components.