Fig. 3: Different implementations of the multi-scale TNF models.
From: PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks

a schematically represents the multi-scale model used to explore the 3T3 fibroblast spheroids growth dynamics under different TNF exposure regimes. b shows the intracellular models used in the PhysiBoSS original publication (left) and the extended version implemented in PhysiBoSS 2.0 (right).