Fig. 4: Average node degrees of each TF among the found MDSTs. | npj Systems Biology and Applications

Fig. 4: Average node degrees of each TF among the found MDSTs.

From: Data-driven structural analysis of small cell lung cancer transcription factor network suggests potential subtype regulators and transition pathways

Fig. 4

FLI1 is the major hub with about 14 connections on average in the found MDSTs. The other hubs are ASCL1, MITF, and MYC with relatively high connectedness on average. We note that MYC emerges as a hub after data integration, which was not the case with the pure structural analysis in Fig. 3.

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