Fig. 8: Frequencies of TFs in the distance decreasing and increasing patterns.

a Appearance of TFs in the distance decreasing patterns. The shaded TFs, i.e., ASCL1, FLI1, NR0B1, and CEBPD, appear more than the other TFs in the distance-decreasing patterns. b Appearance of TFs in the distance increasing patterns. The shaded TFs, i.e., ASCL1, FLI1, NR0B1, and CEBPD, appear less than the other TFs in the distance-increasing patterns.