Table 1 Tools overlapping with concepts also present in Kosmogora+ECellDive.

Tool	Actor	Platform	Field/Subject	Metaverse-Ready^a	Description
Nanome²⁴	Industry	VR	Biology, Chemistry, Pharmaceutics	No	A collaborative tool for molecular design and analysis
VR-Omics^25,62	Academia	Desktop 2D & 3D + VR	Omics data visualization	No	Desktop to VR pipeline integration for omics data processing and visualization
Molecular Rift⁶³	Academia	VR	Biology, Chemistry, Pharmaceutics	No	A tool for molecular structure visualization
Cytoscape³³	Academia	Desktop 2D & 3D (via plug-in)	Network Data (Biology, Social Sciences, …)	No	Popular tool for display and analysis of network data
Graphia⁶⁴	Academia	Desktop 2D & 3D	Network Data (Biology, Agritech, Social Media, …)	No	Tool for display and analysis of large-scale network data
SpaceTime⁶⁵	Academia	VR	Real-time collaboration	No	Research project for new collaboration schemes and techniques in real-time VR
DataHop⁶⁶	Academia	VR	Data visualization	No	Research project for immersed data visualization where plots are laid out according to the analysis steps of the user
NVIDIA Omniverse⁶⁷	Industry	Desktop & XR	Virtual world creation	Yes	Large development tool suite for engineering-grade digital twins (industrial and scientific) and metaverse applications
Volvo Truck R&D¹¹	Industry	Desktop & VR	Automobile engineering R&D	Yes	In-house R&D system for collaborative and immersive design of new trucks

^aMetaverse-Ready means that the tool includes metaverse constraints directly in its specifications; it does not mean that the tool is a Metaverse or is future-proof against the evolution of the definition of the Metaverse. For example, Nanome and VR-Omics are very good immersive visualizations, but they do not include concepts in their architecture to integrate with the larger scale of a Metaverse. NVIDIA Omniverse and the Volvo Truck R&D were designed to support this larger scale, which makes them “metaverse-ready” in our definition.

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