Table 1 List of abbreviations and their full names used in the article
From: A comprehensive review of computational cell cycle models in guiding cancer treatment strategies
Abbreviation | Full Name |
|---|---|
ABMs | Agent-based models |
ANN | Artificial neural network |
APC | Antigen-presenting cell |
BrCa | Breast cancer |
CDKs | Cyclin-dependent kinases |
CFSE | Carboxyfluorescein succinimidyl ester |
CKIs | Cyclin-dependent kinase inhibitors |
DCIS | Ductal carcinoma in situ |
DDR | DNA damage response |
DRL | Deep reinforcement learning |
DSBs | Double-strand breaks |
ECM | Extracellular matrix |
EMT | Epithelial-mesenchymal transition |
FUCCI | Fluorescent ubiquitination-based cell cycle indicator |
HSC | Hematopoietic stem cell |
LET | Linear energy transfer |
mAbs | Monoclonal antibodies |
MAPK | Mitogen-activated protein kinase |
MCMC | Markov chain Monte Carlo |
MIDD | Model-informed drug development |
ML | Machine learning |
MSMs | Multi-stage models |
MTD | Maximum tolerated dose |
NSCLC | Non-small cell lung cancer |
OCT | Optical coherence tomography |
ODEs | Ordinary differential equations |
OvCa | Ovarian cancer |
PaCa | Pancreatic cancer |
PDEs | Partial differential equations |
PPI | Protein-protein interaction |
PSPMs | Physiologically structured population models |
QSP | Quantitative systems pharmacology |
RBF | Radial basis function |
RD | Reaction-diffusion |
RMSE | Root mean square error |
RPIM | Radial point interpolation method |
SDEs | Stochastic differential equations |
SMI | Small-molecule inhibitor |
SPN | Stochastic Petri net |
spQSP | Spatial quantitative systems pharmacology |
SSA | Stochastic simulation algorithm |
SVM | Support vector machine |
TGI | Tumor growth inhibition |
TME | Tumor microenvironment |
VEGF | Vascular endothelial growth factor |
VP | Virtual patient |
WCMs | Whole-cell models |
