Fig. 3: SignalingProfiler 2.0 protein activity inference parameters tuning (Step 1).
From: SignalingProfiler 2.0 a network-based approach to bridge multi-omics data to phenotypic hallmarks
A–C For each parameter, the average Precision, Recall, Number of true positives, and Root Mean Squared Error (RMSE) with respect to the protein gold standard are reported across 64, 32, and 4 conditions for transcription factors (A), kinases/phosphatases (B), and other signaling proteins (C), respectively. Optimal parameter values are reported in red. White and dark gray represent minimum and maximum parameter values.
