Fig. 3: Metadata networks (METNs) based on Origin and Target.

A Origin METN describes the origin of the hemolytic peptides (e.g., synthetic, isolated from Halocynthia aurantium, etc.). The dashed box represents the whole Origin METN whereas the bigger figure represents the central part of the Origin METN that was zoomed in for a better visualization. Blue-green nodes represent peptides while violet nodes represent the origin of the peptides. B Target METN describes the target of the hemolytic peptides (e.g., RBCs, Gram-positive bacteria, etc.) which is useful information when exploring associations between therapeutic and hemolytic activities. The dashed box represents the whole Target METN whereas the bigger figure represents the central part of the Target METN that was zoomed in for a better visualization. Blue-green nodes represent peptides whereas green nodes represent the reported target of the peptides. These networks were visualized in Gephi⁷⁰ using Force Atlas 2 layout⁶⁷ and edited with Inkscape⁷⁴.