Fig. 2: Extracellular and intracellular time-series metabolomics data obtained from cell cultures of wild-type E. coli engineered to overproduce limonene (EcoCTs03) used for model development.
From: Systems biology approach for enhancing limonene yield by re-engineering Escherichia coli
A Reflects the concentrations of extracellular metabolites glucose (Glcex), lactic acid (LACex), and acetic acid (ACEex). B Displays the time-series concentrations of secreted limonene (LIMex). C Shows the concentrations of intracellular metabolites glucose-6-phosphate (G6P), fructose-6-phosphate (F6P), fructose-1,6-biphosphate (F16BP), DHAP + GAP (pool of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate), R5P + Ru5P + X5P (pool of ribose-5-phosphate, ribulose-5-phosphate, and xylulose-5-phosphate), and IPP + DMAPP (pool of isopentenyl pyrophosphate and dimethylallyl pyrophosphate) which are of higher concentrations. D Illustrates the intracellular time-series concentrations of pyruvate (PYR), deoxyxylulose 5-phosphate (DXP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), which are of a lower concentration range. Average values are shown for biological replicates ( ± 1 SD).
