Fig. 3: Study design.

Canonical pathway activation and inhibition in GIM (a) and GA (b). Note: Pathways with obtained z-scores included [z-score > 0: activation (red); z-score < 0: inhibition (green); z-scores from −4 to 6 in (a) and from −6 to 6 in (b)]. Pearsons correlation with linear regression between GIM and GA (c). r = -0.5677 and p < 0.001 in (c).