Fig. 1: Properties and predictions of the ME-model of P. putida KT2440.
From: Model of metabolism and gene expression predicts proteome allocation in Pseudomonas putida
a and b Breakdown of metabolites (a) and reactions (b) in iPpu1676-ME as compared to the template M-model, iJN14621. c Genome coverage of iPpu1676-ME and iJN1462. d Comparison of flux variability analysis of the M- and ME-models of P. putida KT2440. The distribution of the flux ranges is bimodal due to the tolerance of the QuadMINOS solver of 10−16, below which fluxes can vary at a negligible level. e Prediction of the maximum growth rate of P. putida KT2440 by the ME-model as opposed to the overestimation in the M-model, compared to reported maximum growth rates6,21,22,23,24. Area plots show the predicted secretion rates of overflow metabolites acetate and 2-ketogluconate by the ME-model, which the M-model does not predict.
