Table 3 Added edges in the GA-refined models compared to the 2017 model29

From: Automated model refinement using perturbation-observation pairs

 

PA ABI2

Aquaporin → ROS

ROS → AR

PA → MD

pHc → VA

Other Edges

Maheshwari 2019

O

X

X

X

X

 

GA 1-A

O

O

O

O

O

PA HAB1

GA 1-B

O

O

O

O

O

Ca2+c osc ABI2

AR → RBOH

  1. AR Actin reorganization, MD Microtubule depolymerization, VA Vacuolar acidification.
  2. The notation “→” means activation and “” means inhibition. Note that the inhibitory edge from PA to ABI2, which was incorporated in the 2019 revision of that model by Maheshwari et al.30, was added by both GA-refined models.