Fig. 2: Elevated noise increases relapse risk at fixed treatment threshold.
From: The effect of stochastic noise on antibiotic resistance in intestinal flora
a–c Depicted the time evolution of pathogen numbers, normalized to Ω, during this process for Ω = 2000 (a), Ω = 5000 (b), and Ω = 10,000 (c), each showing 20 time-courses. The gray curve represented the pathogen number over time in the ODE model, while the red, cyan, and blue curves illustrated the infection, antibiotic-treatment, and recovery phases in the stochastic model, respectively. The inset figures showed the distribution of treatment durations across 10,000 simulations. d Demonstrated the probability of disease relapse following a single treatment at a fixed treatment threshold, based on the results of 10,000 simulations for each noise intensity level.
