Fig. 1: Overview diagram of the spectrum formation approach (SFA). | npj Systems Biology and Applications

Fig. 1: Overview diagram of the spectrum formation approach (SFA).

From: Utility of the continuous spectrum formed by pathological states in characterizing disease properties

Fig. 1

A The SFA is devised to extract information that is prioritized in the SFC. For a given dataset, the GC and SFC are constructed and evaluated the feature importance separately. The differences between GC and SFC was focused on. B SFA enables knowledge-guided analysis by allowing researchers to define conceptual relationships between states (e.g., through overlap weights), in contrast to conventional classification analyses, which are entirely data-driven.

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