Fig. 4 | npj Vaccines

Fig. 4

From: Alpha-D-glucan nanoparticulate adjuvant induces a transient inflammatory response at the injection site and targets antigen to migratory dendritic cells

Fig. 4

Nano-11 is actively transported by APCs to the draining lymph node. a Detection and phenotyping of Nano-11-containing myeloid cells at different time points in the draining lymph node. Data are representative of three independent experiments. b Percentage of Nano-11-containing cells among all myeloid cells in the draining lymph node over time. Mean ± SEM of three mice; *significantly different from day 1 and day 7 (p < 0.05) c Distribution of Nano-11 in different subtypes of APCs in the draining lymph node over time. Mean ± SEM of three mice; * and ** significantly different from the other two groups (p < 0.01). d Uptake of Nano-11 per cell for each APC subtype as indicated by the mean fluorescence intensity (MFI). Mean ± SEM of three mice; *p < 0.01

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