npj Vaccines

Table 1 Viral titers in collected swab and tissue samples from experimental chickens. (A) Viral titers in oropharyngeal and cloacal swabs collected from vaccinated and mock-vaccinated chickens at 1, 3, 5, 7, and 9 days post challenge; (B) Viral titers in different tissues collected from vaccinated or mock-vaccinated chickens at different days post challenge

From: Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus

	1 dpc		3 dpc		5 dpc		7 dpc		9 dpc
	Oropharyngeal	Cloacal	Oropharyngeal	Cloacal	Oropharyngeal	Cloacal	Oropharyngeal	Cloacal	Oropharyngeal	Cloacal
(A)
Live NDV-H5	1.7^a (1/20)^b	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0
Inactivated NDV-H5	2.5 ± 0^a (2/15)^b	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0
Mock-vaccinated	2.43 ± 0.18^a (9/15)^b	<1.0	3.18 ± 0.31^a (8/8)^b	1.7 ± 0^a (2/8)^b	N/A	N/A	N/A	N/A	N/A	N/A

	Lung		Spleen		Bursa
	3 dpc	5 dpc	3 dpc	5 dpc	3 dpc	5 dpc
(B)
Live NDV-H5	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0
Inactivated NDV-H5	<1.0	<1.0	<1.0	<1.0	<1.0	<1.0
Mock-vaccinated	3.7 ± 0.35^a (7/8)^b	N/A	2.86 ± 0.46^a (5/8)^b	N/A	3.67 ± 0.36^a (7/8)^b	N/A

N/A none applicable. Chickens were dead before the samples collection days
^a Log₁₀ TCID₅₀/mL
^b Positive bird numbers out of total numbers

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