Table 2 Histopathology scores of tissues collected from vaccinated and mock-vaccinated chickens at 3 and 4/5 dpc

From: Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus

 

3 dpc

4/5a dpc

 

Spleen

Bursa

Lung

Spleen

Bursa

Lung

Live NDV-H5

0 (0/5)

0 (0/5)

0.2 ± 0.22 (1/5)b

0 (0/5)

0 (0/5)

0 (0/5)

Inactivated NDV-H5

0 (0/4)

0 (0/4)

0.25 ± 0.25 (1/4)b

0 (0/4)

0 (0/4)

0 (0/4)

Mock-vaccinatedc

2.8 ± 0.2 (5/5)d

2.6 ± 0.24 (5/5)d

2.8 ± 0.2 (5/5)d

3 (1/1)c

3 (1/1)c

2 (1/1)c

  1. a For the mock-vaccinated group, the tissues were collected from birds on 4 dpc; and for both vaccine groups, they were collected on 5 pdc
  2. b The sample was positive in pathology but negative in IHC
  3. c Three of the mock birds’ tissue sets could not be scored because interpretation of histopathology was hampered by autolysis. Sample set collected at 4 dpc
  4. d Positive bird numbers out of total numbers
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