Fig. 3 | npj Vaccines

Fig. 3

From: Design and production of conjugate vaccines against S. Paratyphi A using an O-linked glycosylation system in vivo

Fig. 3

Analysis and immune effect evaluation of CTB4573-OPS in mice. a Coomassie blue staining of purified CTB4573-OPS. b Analysis of purified CTB4573-OPS by size-exclusion high-performance liquid chromatography (TSK G4000SWXL, diameter, 7.8 × 300 mm) (up) and reversed-phase high-performance liquid chromatography (Agilent ZORBAX 300SB-C8, diameter, 4.6 × 250 mm) (down). c IgG subclass titers (IgG1, IgG2a, IgG2b, and IgG3) against LPSs from six S. Paratyphi A strains were measured in serum from CTB4573-OPS immunized mice. A t-test was used to evaluate differences between IgG1 titer and other subclass titers (***P < 0.001). Error bars indicate the standard deviation

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