Fig. 3: RSV-F-specific IFNγ ELISPOT responses.

IFNγ ELISPOT responses in PBMC were determined after stimulation with a pool of 15-mer peptides overlapping by 11 amino acids, covering the RSV-F protein sequence. a–c Shown are background subtracted values per animal receiving a homologous prime-boost with the Ad26/Ad35 mix a, a homologous prime-boost with Ad26 b, or a heterologous prime-boost with Ad26 and Ad35 c. Dotted line = assay threshold based on CV, at 50 SFU/106 cells. Red bars depict geometric group means.