Fig. 4: Dose dependent induction of IgG and transmission-reducing activity following immunization of Pfs230C1 with CoPoP/PHAD liposomes.
From: Antibody response of a particle-inducing, liposome vaccine adjuvant admixed with a Pfs230 fragment
a IgG titer as a function of Pfs230C1 injection doses in mice. All dots represented geometric mean titers from n = 10 mice. b Percentage of TRA to anti-Pfs230 IgG level in feeder and (c) LMR to anti-Pfs230C1 IgG level in feeder (square root scale). Each dot represents purified IgG from n = 10 mice. Oocytes were counted and percentage of transmission-reducing activity or the log mean ratio of the oocyst count (of the test sample compared to the positive control) were calculated from n = 20 mosquitos.
